Abstract | OBJECTIVE: METHODS: Forty male Sprague-Dawley rats were fed a high-fat diet for 4 wk to induce NASH and then were allocated to one of four diets: a NASH-inducing diet, a standard diet, a NASH-inducing diet plus soy protein, and a standard diet plus soy protein. RESULTS: CONCLUSION:
Soy protein may improve the liver function in patients with NASH by lowering lipid levels in the blood and liver, increasing the antioxidative capacity, and improving insulin resistance.
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Authors | Hsin-Yi Yang, Ya-Hui Tzeng, Chiah-Yang Chai, An-Tsz Hsieh, Jiun-Rong Chen, Le-Shin Chang, Sien-Sing Yang |
Journal | Nutrition (Burbank, Los Angeles County, Calif.)
(Nutrition)
Vol. 27
Issue 9
Pg. 943-8
(Sep 2011)
ISSN: 1873-1244 [Electronic] United States |
PMID | 21333494
(Publication Type: Journal Article)
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Copyright | Copyright © 2011 Elsevier Inc. All rights reserved. |
Chemical References |
- Antioxidants
- Dietary Fats
- Soybean Proteins
- Triglycerides
- Cholesterol
- Catalase
- Cytochrome P-450 CYP2E1
- Superoxide Dismutase
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Topics |
- Adipose Tissue
(metabolism)
- Animals
- Antioxidants
(metabolism)
- Catalase
(metabolism)
- Cholesterol
(metabolism)
- Cytochrome P-450 CYP2E1
(metabolism)
- Dietary Fats
(adverse effects)
- Disease Progression
- Fatty Liver
(diet therapy, etiology, metabolism)
- Insulin Resistance
- Lipid Metabolism
(drug effects)
- Lipid Peroxidation
(drug effects)
- Liver
(drug effects, metabolism)
- Male
- Non-alcoholic Fatty Liver Disease
- Phytotherapy
- Rats
- Rats, Sprague-Dawley
- Soybean Proteins
(pharmacology, therapeutic use)
- Soybeans
(chemistry)
- Superoxide Dismutase
(metabolism)
- Triglycerides
(metabolism)
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