Abstract | OBJECTIVE: MATERIALS AND METHODS: Patients diagnosed with stages I-II S-CC and CS after comprehensive surgical staging were retrospectively collected. Surgical staging was defined as pelvic lymphadenectomy of more than 11 nodes harvested and exploration of the upper abdomen, with our without omentectomy. Groups with (group A) and without (group B) platinum-based chemotherapy were compared. RESULTS: We identified 69 patients with a mean age of 66 years (range, 48-88 years). Both groups showed similar baseline characteristics. Group A consisted of 34 patients (23 S-CC, 11 CS) with 10 (29%) recurrences outside the pelvis (7 S-CC, 3 CS). Group B included 35 patients (28 S-CC, 7 CS) of which 10 (29%) developed recurrence outside the pelvis (7 S-CC, 3 CS). The median recurrence-free survival was 22 months (range, 13-51 months) for group A versus 10 months (range, 1-59 months) for group B (P = 0.437). Five patients (15%) of group A and 9 (26%) of group B died of disease after a median follow-up of 29 months (range, 20-59 months) and 17 months (range, 4-64 months), respectively (P = 0.168). CONCLUSION:
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Authors | Ingrid Vandenput, Jone Trovik, Ignace Vergote, Philippe Moerman, Karin Leunen, Patrick Berteloot, Patrick Neven, Helga Salvesen, Frédéric Amant |
Journal | International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
(Int J Gynecol Cancer)
Vol. 21
Issue 2
Pg. 332-6
(Feb 2011)
ISSN: 1525-1438 [Electronic] England |
PMID | 21270614
(Publication Type: Journal Article, Multicenter Study)
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Chemical References |
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Topics |
- Adenocarcinoma, Clear Cell
(drug therapy, pathology, surgery)
- Aged
- Aged, 80 and over
- Antineoplastic Agents
(administration & dosage)
- Carcinosarcoma
(drug therapy, pathology, surgery)
- Chemotherapy, Adjuvant
- Cystadenocarcinoma, Serous
(drug therapy, pathology, surgery)
- Endometrial Neoplasms
(drug therapy, pathology, surgery)
- Female
- Humans
- Middle Aged
- Neoplasm Recurrence, Local
(prevention & control)
- Neoplasm Staging
- Retrospective Studies
- Survival Analysis
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