Preventive effects of an immunostimulating product on recurrent infections of chronic bronchitis in the elderly.

Abstract

The effect of an immunostimulating drug, OM-85 BV, was demonstrated on recurrent infection rates in 265 elderly patients with a defined state of chronic bronchitis, during a 6-month, double-blind, placebo-controlled trial. Patients receiving OM-85 BV presented less infections (p = 0.005) and a significantly reduced intake of antibiotics (p = 0.02) as compared to those receiving a placebo and the antibiotic intake was significantly reduced (p = 0.02).

• Authors: N Debbas, J P Derenne
• Journal: Lung (Lung) Vol. 168 Suppl Pg. 737-40 ( 1990) ISSN: 0341-2040 [Print] United States
• PMID: 2117186 (Publication Type: Clinical Trial, Journal Article, Multicenter Study, Randomized Controlled Trial)

Chemical References

• Adjuvants, Immunologic
• Broncho-Vaxom
• Cell Extracts

Topics

• Adjuvants, Immunologic (administration & dosage)
• Administration, Oral
• Aged
• Aged, 80 and over
• Bacteria
• Bronchitis (immunology, therapy)
• Cell Extracts
• Chronic Disease
• Double-Blind Method
• Female
• Humans
• Immune Tolerance (drug effects)
• Male
• Multicenter Studies as Topic
• Randomized Controlled Trials as Topic
• Respiratory Tract Infections (immunology, therapy)