[Therapeutic strategy for secondary lung cancer].

Abstract

Among 659 resected lung cancer cases from 1994 to 2009, 57 secondary lung cancers (8.6%) were evaluated. The secondary tumors were synchronous, located in the same lobe in 10, the ipsilateral different lobe in 17, and the contralateral lobe in 13, or metachronous, located in the contralateral lobe in 15, and the ipsilateral different lobe in 5. Both the tumors were removed in 49 cases. Chemotherapy, stereotactic radiotherapy (SRT), photo dynamic therapy (PDT), or best supportive care (BSC) was selected after a lobectomy or segmentectomy of the 1st tumor in 8 cases considering the patient's condition. Lobectomy or segmentectomy should be indicated for the 1st tumor considering curability. Bilobectomy is adopted for multiple cancers involving middle lobe. According to the operability or pulmonary function, the same strategy is adopted for secondary cancer. Considering the patient's condition, possibility of metastases and the tumor location and histologic type, partial resection, SRT, PDT, or BSC could be selected.

• Authors: Hiroyuki Miura, Norio Nakajima, Hidenobu Takahashi, Masao Kinoshita, Norihiko Ikeda
• Journal: Kyobu geka. The Japanese journal of thoracic surgery (Kyobu Geka) Vol. 63 Issue 11 Pg. 956-61 (Oct 2010) ISSN: 0021-5252 [Print] Japan
• PMID: 20954350 (Publication Type: English Abstract, Journal Article)

Topics

• Adult
• Aged
• Aged, 80 and over
• Female
• Humans
• Lung Neoplasms (surgery)
• Male
• Middle Aged
• Neoplasms, Multiple Primary (surgery)
• Neoplasms, Second Primary (surgery)
• Pneumonectomy