High-frequency electrocardiogram as a supplement to standard 12-lead ischemia monitoring during reperfusion therapy of acute inferior myocardial infarction.

Abstract

BACKGROUND:

Resolution of ST-segment elevation in the electrocardiogram (ECG) is used as a reperfusion sign during thrombolytic therapy in acute myocardial infarction. Analysis of high-frequency QRS components (HF-QRS) might provide additional information. The study compares changes in HF-QRS (150-250 Hz) to ST-segment changes in the standard ECG during thrombolytic therapy.

METHODS:

Twelve patients receiving intravenous thrombolytic therapy were included. A continuous 12-lead ECG recording was acquired for 4 hours.

RESULTS:

After 1 hour of therapy, 3 patients showed ST-elevation resolution as well as an increase in HF-QRS. These changes in ST and HF-QRS occurred simultaneously. No other patient showed significant changes in ST or HF-QRS after 1 hour. After 2 and 4 hours, there was less concordance between the standard and high-frequency ECGs.

CONCLUSIONS:

In patients with early ST-elevation resolution, the standard and high-frequency ECGs show similar results. Later changes are more disparate and may provide different clinical information.

• Authors: Jonas Pettersson, Galen S Wagner, Leif Sörnmo, Elin Trägårdh Johansson, Hans Ohlin, Olle Pahlm
• Journal: Journal of electrocardiology (J Electrocardiol) 2011 Jan-Feb Vol. 44 Issue 1 Pg. 11-7 ISSN: 1532-8430 [Electronic] United States
• PMID: 20488451 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: Copyright © 2011 Elsevier Inc. All rights reserved.

Topics

• Aged
• Aged, 80 and over
• Electrocardiography (methods)
• Female
• Humans
• Male
• Middle Aged
• Myocardial Infarction (diagnosis, therapy)
• Myocardial Reperfusion (methods)
• Reproducibility of Results
• Sensitivity and Specificity
• Thrombolytic Therapy (methods)
• Treatment Outcome