Association of environmental tobacco smoke exposure with elevated home blood pressure in Japanese women: the Ohasama study.

Abstract

OBJECTIVE:

Only a few of numerous epidemiological studies have demonstrated a positive association between environmental tobacco smoke (ETS) exposure and blood pressure (BP), despite experimental studies showing such a positive association. The association between home blood pressure (HBP) and ETS exposure was investigated in the general population.

METHODS:

Five hundred and seventy-nine nonsmoking Japanese women were enrolled. The participants were classified into four categories according to their responses to a self-administered questionnaire: unexposed women (non-ETS), women exposed at home [ETS(home)], at the workplace/other places [ETS(work/other)] and at home and at the workplace/other places [ETS(both)]. Variables were compared using analysis of covariance adjusted for age, marital status, body mass index, diabetes mellitus, stroke, heart disease, hyperlipidemia, alcohol intake, salt intake and activity levels.

RESULTS:

In participants without antihypertensive medication, systolic morning HBP in ETS(both) was 4 mmHg higher than that in non-ETS (116.8 +/- 1.01 vs. 113.1 +/- 1.08 mmHg, P = 0.02) and systolic morning HBP in ETS(home) and systolic evening HBP in ETS(both) were 3 mmHg higher than those in non-ETS (116.2 +/- 1.07 vs. 113.1 +/- 1.08 mmHg, P = 0.04; and 115.3 +/- 1.02 vs. 111.9 +/- 1.09 mmHg, P = 0.03, respectively). In participants with antihypertensive medication, ETS exposure status was not significantly associated with increased HBP levels.

CONCLUSIONS:

A positive association between HBP levels and ETS exposure was confirmed. HBP measurement is recommended in population-based studies investigating the effects of ETS exposure. ETS exposure may increase BP, thereby synergistically contributing to unfavorable cardiovascular outcomes along with other deleterious effects of ETS.

• Authors: Mami Seki, Ryusuke Inoue, Takayoshi Ohkubo, Masahiro Kikuya, Azusa Hara, Hirohito Metoki, Takuo Hirose, Megumi Tsubota-Utsugi, Kei Asayama, Atsuhiro Kanno, Taku Obara, Haruhisa Hoshi, Kazuhito Totsune, Hiroshi Satoh, Yutaka Imai
• Journal: Journal of hypertension (J Hypertens) Vol. 28 Issue 9 Pg. 1814-20 (Sep 2010) ISSN: 1473-5598 [Electronic] Netherlands
• PMID: 20453668 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Antihypertensive Agents
• Tobacco Smoke Pollution

Topics

• Adult
• Aged
• Antihypertensive Agents (therapeutic use)
• Asian People
• Blood Pressure (drug effects)
• Blood Pressure Monitoring, Ambulatory
• Environmental Exposure
• Female
• Heart Rate (drug effects)
• Humans
• Hypertension (drug therapy, epidemiology, etiology, physiopathology)
• Japan (epidemiology)
• Middle Aged
• Occupational Exposure
• Tobacco Smoke Pollution (adverse effects)