[Lobectomy for local recurrence following stereotactic radiotherapy to non-small cell lung cancer].

Abstract

A 78-year-old man had non-small cell lung cancer (NSCLC) in the left upper lobe (squamous cell carcinoma, cT1N0M0). He preferred less invasive treatment and undertook stereotactic radiotherapy (SRT)[48 Gy/4 Fr] because his forced expiratory volume in 1 second percent (FEV1.0%) was 53.50%. The therapeutic effect was partial response and the adverse reaction was dermatitis (grade 1). Seven months after SRT, local recurrence was detected. The tumor was growing from 3 x 5 mm to 25 x 25 mm in size. Nine months after SRT, left upper lobectomy was performed successfully unaffected by SRT. He is doing well 14 months after the operation without any signs of recurrence. This case might help develop a new strategy for the treatment of stage I NSCLC. It is that patients with stage I NSCLC have SRT as 1st line treatment, and if local recurrence is observed after SRT, lobectomy may be performed.

• Authors: S Neri, J Kitamura, T Komatsu, Y Takahashi, Y Takeshima, R Kaji, M Hayashi, T Nishimura, K Tomii, N Katakami, K Ishihara, M Kokubo
• Journal: Kyobu geka. The Japanese journal of thoracic surgery (Kyobu Geka) Vol. 62 Issue 9 Pg. 812-5 (Aug 2009) ISSN: 0021-5252 [Print] Japan
• PMID: 19670785 (Publication Type: Case Reports, English Abstract, Journal Article)

Topics

• Aged
• Carcinoma, Non-Small-Cell Lung (radiotherapy, surgery)
• Humans
• Lung Neoplasms (radiotherapy, surgery)
• Male
• Neoplasm Recurrence, Local (surgery)
• Pneumonectomy
• Stereotaxic Techniques