Case report: severe neonatal hyperkalemia due to pseudohypoaldosteronism type 1.

Abstract

Hyponatremia and hyperkalemia in infancy can represent a variety of renal and genetic disorders with significant long-term health implications. We report a newborn with severe hyperkalemia and hyponatremia from autosomal recessive pseudohypoaldosteronism type 1 requiring aggressive therapy. The evaluation and treatment of children with disorders of mineralocorticoid action are discussed.

• Authors: Bahareh Schweiger, Margaret W Moriarty, Melissa A Cadnapaphornchai
• Journal: Current opinion in pediatrics (Curr Opin Pediatr) Vol. 21 Issue 2 Pg. 269-71 (Apr 2009) ISSN: 1531-698X [Electronic] United States
• PMID: 19657313 (Publication Type: Case Reports, Journal Article)

Chemical References

• Citrates
• Epithelial Sodium Channels
• Mineralocorticoids
• Sodium Citrate
• Sodium Chloride
• Aldosterone
• Renin
• Potassium
• Fludrocortisone

Topics

• Aldosterone (blood)
• Citrates (therapeutic use)
• Dietary Supplements
• Electrocardiography
• Epithelial Sodium Channels (genetics)
• Female
• Fludrocortisone (therapeutic use)
• Humans
• Hyperkalemia (blood, diagnosis, genetics, therapy)
• Infant, Newborn
• Mineralocorticoids (therapeutic use)
• Mutation
• Potassium (blood, urine)
• Pseudohypoaldosteronism (blood, diagnosis, genetics, therapy)
• Renin (blood)
• Sodium Chloride (therapeutic use)
• Sodium Citrate