Evaluation of different fluoride treatments of initial root carious lesions in vivo.

Abstract

PURPOSE:

The aim of this study was to evaluate the efficacy of three topical fluoride treatments to arrest initial root carious lesions.

MATERIALS AND METHODS:

Forty patients participated in a randomised study. Of the 60 root carious lesions that were included, 20 were randomised for treatment with the Carisolv chemo-mechanical technique and the Duraphat (2.23% F) fluoride varnish, 20 with Duraphat alone and 20 with stannous fluoride solution (8%). The lesions were treated at baseline and after three and six months; a clinical evaluation was carried out on these occasions and after 1 year.

RESULTS:

All but four lesions were categorised as arrested caries during the 1-year follow-up period: 18 in the Carisolv/Duraphat group and 19 each in the Duraphat and the stannous fluoride groups, respectively. There was a minor reduction in the mean size of the lesions of around 0.1 to 0.2 mm height and width and a moderate change in colour from a lighter to a darker appearance. No obvious differences were found between the groups. The mean percentage of mutans streptococci in plaque from all lesions was 3.5% at baseline, and it decreased to 1.8% during the year. The decrease was, however, not statistically significant, and no significant differences were found between the groups.

CONCLUSIONS:

It can be concluded that the frequent topical application of fluoride could be a successful treatment for incipient root carious lesions, irrespective of the type of fluoride treatment used.

• Authors: Solveig Fure, Peter Lingström
• Journal: Oral health & preventive dentistry (Oral Health Prev Dent) Vol. 7 Issue 2 Pg. 147-54 ( 2009) ISSN: 1602-1622 [Print] Germany
• PMID: 19583040 (Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)

Chemical References

• Cariostatic Agents
• Carisolv
• Fluorides, Topical
• Tin Fluorides
• sodium fluoride topical preparation
• Glutamic Acid
• Sodium Fluoride
• Leucine
• Lysine

Topics

• Adult
• Aged
• Aged, 80 and over
• Cariostatic Agents (therapeutic use)
• Colony Count, Microbial
• Dental Cavity Preparation
• Dental Plaque (microbiology)
• Dentin (pathology)
• Female
• Fluorides, Topical (therapeutic use)
• Follow-Up Studies
• Glutamic Acid (therapeutic use)
• Humans
• Leucine (therapeutic use)
• Lysine (therapeutic use)
• Male
• Middle Aged
• Prospective Studies
• Root Caries (prevention & control, therapy)
• Saliva (metabolism, microbiology)
• Single-Blind Method
• Sodium Fluoride (therapeutic use)
• Streptococcus mutans (isolation & purification)
• Tin Fluorides (therapeutic use)
• Tooth Remineralization
• Treatment Outcome