Abstract | BACKGROUND: OBJECTIVE: We sought to determine whether exposure to nbUVB reduces folate levels. METHODS: This single-center, open observational study was conducted in a teaching hospital setting. Serum and red cell folate levels were measured in patients with psoriasis attending for nbUVB at baseline and after a minimum of 18 exposures. RESULTS: A total of 35 patients completed the study. Mean serum and red cell folate levels at baseline were 6.34 and 410 ng/ml, respectively. After nbUVB, mean serum and red cell folate levels were 6.35 and 423 ng/ml, respectively. This was not significantly different from baseline measurements (P = .99 serum folate and P = .57 red cell folate). LIMITATIONS: This study examined the effect of a standard course of 18 exposures of nbUVB on folate levels, rather than prolonged treatment. Adult patients with psoriasis only were investigated. CONCLUSION: A standard course of nbUVB does not have an effect on serum and red cell folate levels in patients with psoriasis.
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Authors | Rebecca F Rose, Rebecca J Batchelor, David Turner, Victoria Goulden |
Journal | Journal of the American Academy of Dermatology
(J Am Acad Dermatol)
Vol. 61
Issue 2
Pg. 259-62
(Aug 2009)
ISSN: 1097-6787 [Electronic] United States |
PMID | 19493587
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
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Topics |
- Adult
- Aged
- Biomarkers
(blood)
- Cohort Studies
- Female
- Folic Acid
(blood, metabolism)
- Follow-Up Studies
- Humans
- Male
- Middle Aged
- Probability
- Psoriasis
(blood, diagnosis, radiotherapy)
- Risk Assessment
- Severity of Illness Index
- Treatment Outcome
- Ultraviolet Therapy
(methods)
- Young Adult
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