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[A case of locally advanced rectal cancer responding to FOLFOX].

Abstract
The 57-year-old man was underwent sigmoid colostomy due to unresectable rectal carcinoma. Then he was treated with chemotherapy of levofolinate/5-fluorouracil/oxaliplatin(FOLFOX). After completion of 12 courses of chemotherapy, MR revealed responses. The patient underwent a low anterior resection. Preoperative chemotherapy with FOLFOX appears a promising regimen for patients with unresectable rectal cancer.
AuthorsShuichi Kume, Tatsuo Kubota, Masafumi Takahashi, Daisuke Hashimoto, Takafumi Hirata, Yoshitsugu Torigoe, Osamu Ikeda
JournalGan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 36 Issue 4 Pg. 659-61 (Apr 2009) ISSN: 0385-0684 [Print] Japan
PMID19381043 (Publication Type: Case Reports, English Abstract, Journal Article)
Chemical References
  • Organoplatinum Compounds
  • Leucovorin
  • Fluorouracil
Topics
  • Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
  • Fluorouracil (therapeutic use)
  • Humans
  • Leucovorin (therapeutic use)
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Neoplasm Invasiveness (pathology)
  • Neoplasm Staging
  • Organoplatinum Compounds (therapeutic use)
  • Proctoscopy
  • Rectal Neoplasms (drug therapy, pathology, surgery)

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