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Community based parasitic screening and treatment of Sudanese refugees: application and assessment of Centers for Disease Control guidelines.

Abstract
Centers for Disease Control guidelines for schistosomiasis and strongyloidiasis in Sudanese and Somali refugees are not widely implemented. Given limited prevalence data, we conducted a seroprevalence study of schistosomiasis, strongyloidiasis, and loiasis in Sudanese refugees across diverse ages. Sudanese refugees, ages 4-78, were recruited via community organizations. Half of the patients (86/172), were seropositive for schistosomiasis (46/171; 26.9%), strongyloidiasis (56/172; 33%), or both (16/171; 9.4%). No Loa loa infections were detected. Infection rates were similar in adults and children except that no schistosomiasis was detected in children < 4 years of age at the time of immigration to the United States. The high prevalence of schistosomiasis and strongyloidiasis in a community-based sample of Sudanese confirms the urgency for compliance with CDC refugee health guidelines. We detected no co-infection with Loa loa using the most sensitive serologic techniques, allowing use of ivermectin, the most effective treatment of strongyloidiasis.
AuthorsStephanie K Brodine, Anne Thomas, Robert Huang, Judith Harbertson, Sanjay Mehta, John Leake, Thomas Nutman, Kathleen Moser, Jamie Wolf, Roshan Ramanathan, Peter Burbelo, John Nou, Patricia Wilkins, Sharon L Reed
JournalThe American journal of tropical medicine and hygiene (Am J Trop Med Hyg) Vol. 80 Issue 3 Pg. 425-30 (Mar 2009) ISSN: 1476-1645 [Electronic] United States
PMID19270293 (Publication Type: Journal Article, Research Support, N.I.H., Intramural, Research Support, Non-U.S. Gov't)
Chemical References
  • Anthelmintics
  • Ivermectin
  • Albendazole
Topics
  • Adolescent
  • Adult
  • Aged
  • Albendazole (economics, therapeutic use)
  • Anthelmintics (economics, therapeutic use)
  • Centers for Disease Control and Prevention, U.S.
  • Child
  • Child, Preschool
  • Cross-Sectional Studies
  • Female
  • Helminthiasis (diagnosis, drug therapy, ethnology)
  • Humans
  • Ivermectin (economics, therapeutic use)
  • Male
  • Middle Aged
  • Practice Guidelines as Topic
  • Refugees
  • Seroepidemiologic Studies
  • Sudan (ethnology)
  • United States
  • Young Adult

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