Catecholamine-secreting neuroblastoma in a 4-month-old infant: perioperative management.

Abstract

Preoperative alpha- and beta-adrenergic receptor block with phenoxybenzamine and labetalol, the intraoperative course of a 4-month-old infant with neuroblastoma and elevated catecholamines causing sweating, hypertension, and tachycardia, are presented. We recommend determination of catecholamine levels and pretreatment with alpha-adrenergic and--if needed--beta-adrenergic receptor antagonists in infants with neuroblastoma and hypertension, tachycardia, or sweating.

• Authors: Michael R Hernandez, Robert C Shamberger, Christian Seefelder
• Journal: Journal of clinical anesthesia (J Clin Anesth) Vol. 21 Issue 1 Pg. 54-6 (Feb 2009) ISSN: 1873-4529 [Electronic] United States
• PMID: 19232942 (Publication Type: Case Reports, Journal Article)

Chemical References

• Adrenergic alpha-Antagonists
• Adrenergic beta-Antagonists
• Catecholamines
• Phenoxybenzamine
• Labetalol

Topics

• Adrenergic alpha-Antagonists (therapeutic use)
• Adrenergic beta-Antagonists (therapeutic use)
• Catecholamines (metabolism)
• Female
• Humans
• Hypertension (etiology)
• Infant
• Labetalol (therapeutic use)
• Neuroblastoma (metabolism, physiopathology, surgery)
• Perioperative Care (methods)
• Phenoxybenzamine (therapeutic use)
• Sweating
• Tachycardia (etiology)