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Neuroblastoma

A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
Also Known As:
Neuroblastomas
Networked: 26260 relevant articles (1114 outcomes, 4057 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Neoplasms (Cancer)
2. Neuroblastoma
3. Neoplasm Metastasis (Metastasis)
4. Glioma (Gliomas)
5. Breast Neoplasms (Breast Cancer)

Experts

1. Maris, John M: 178 articles (12/2022 - 04/2003)
2. Cheung, Nai-Kong V: 113 articles (01/2022 - 05/2002)
3. Matthay, Katherine K: 108 articles (12/2022 - 04/2002)
4. Cohn, Susan L: 97 articles (12/2022 - 01/2002)
5. London, Wendy B: 95 articles (12/2022 - 10/2004)
6. Kogner, Per: 93 articles (01/2022 - 02/2002)
7. Eggert, Angelika: 90 articles (10/2022 - 03/2002)
8. Speleman, Frank: 85 articles (01/2022 - 01/2003)
9. Schulte, Johannes H: 83 articles (04/2022 - 01/2005)
10. Fischer, Matthias: 79 articles (10/2022 - 07/2004)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Neuroblastoma:
1. 3-Iodobenzylguanidine (Iobenguane)IBA
2. dinutuximabIBA
3. Proteins (Proteins, Gene)FDA Link
4. Monoclonal AntibodiesIBA
5. Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
6. Cisplatin (Platino)FDA LinkGeneric
7. Etoposide (VP 16)FDA LinkGeneric
8. Interleukin-2 (IL2)IBA
9. Cyclophosphamide (Cytoxan)FDA LinkGeneric
10. Tretinoin (Retinoic Acid)FDA LinkGeneric

Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
3. Immunotherapy
4. Radiotherapy
5. Bone Marrow Transplantation (Transplantation, Bone Marrow)