Abstract | UNLABELLED: PERSPECTIVE: The findings of this study distinguish between the neuropathic pain syndromes produced by members of a single chemical class of anticancer drugs and suggest that the underlying mechanisms of various forms of peripheral neuropathy may be different. Further, it defines the need for selective therapy for different types of neuropathy.
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Authors | Elizabeth K Joseph, Jon D Levine |
Journal | The journal of pain
(J Pain)
Vol. 10
Issue 5
Pg. 534-41
(May 2009)
ISSN: 1528-8447 [Electronic] United States |
PMID | 19231296
(Publication Type: Comparative Study, Journal Article, Research Support, N.I.H., Extramural)
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Chemical References |
- Antineoplastic Agents
- Organoplatinum Compounds
- Oxaliplatin
- Caspases
- Cisplatin
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Topics |
- Animals
- Antineoplastic Agents
- Behavior, Animal
(drug effects)
- Caspases
(physiology)
- Cisplatin
- Cold Temperature
- Dose-Response Relationship, Drug
- Electron Transport
(drug effects)
- Hot Temperature
- Hyperalgesia
(chemically induced, psychology)
- Male
- Mitochondria
(drug effects, metabolism)
- Organoplatinum Compounds
- Oxaliplatin
- Pain
(chemically induced)
- Pain Measurement
(drug effects)
- Peripheral Nervous System Diseases
(chemically induced)
- Physical Stimulation
- Rats
- Rats, Sprague-Dawley
- Second Messenger Systems
(drug effects)
- Signal Transduction
(drug effects, physiology)
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