Metastatic uterine leiomyosarcoma presenting as a breast lump.

Abstract

BACKGROUND:

It is uncommon to encounter a breast metastasis from an extramammary malignancy and even rarer from a uterine leiomyosarcoma.

AIMS:

We describe the third case report in the medical literature of a breast metastasis from a uterine leiomyosarcoma.

METHODS:

We report the management of a 56-year-old patient who presented with a breast lump 3 years after hysterectomy for a fibroid uterus. We conducted a literature review of breast leiomyosarcomas.

RESULTS:

The excision of the breast mass revealed a low-grade leiomyosarcoma. Radiographic examinations demonstrated metastases to the lung, liver, pelvis and bone. Retrospective pathology review of her uterus identified a small focus of leiomyosarcoma. She received chemotherapy and palliative radiotherapy but passed away within few months.

CONCLUSION:

Metastasis to the breast from a non-breast primary is generally a sign of disseminated disease and; thus, a poor prognostic indicator.

• Authors: S Sibartie, J O Larkin, G Lee, J Fitzgibbon, S O'Reilly, D Richardson
• Journal: Irish journal of medical science (Ir J Med Sci) Vol. 180 Issue 4 Pg. 889-91 (Dec 2011) ISSN: 1863-4362 [Electronic] Ireland
• PMID: 19184604 (Publication Type: Case Reports, Journal Article)

Topics

• Bone Neoplasms (secondary)
• Breast Neoplasms (diagnosis, secondary, therapy)
• Chemotherapy, Adjuvant
• Fatal Outcome
• Female
• Humans
• Leiomyosarcoma (diagnosis, secondary, therapy)
• Liver Neoplasms (secondary)
• Lung Neoplasms (secondary)
• Middle Aged
• Pelvic Neoplasms (secondary)
• Uterine Neoplasms (pathology)