Abstract |
A 62 year-old female hemodialysis patient underwent parathyroidectomy to treat secondary hyperparathyroidism. On the preoperative assessment, the plasma levels of parathyroid hormone (PTH) and B-type natriuretic peptide (BNP) were elevated. Echocardiography showed reduced left ventricular (LV) contraction. Myocardial iodine-123-15-(p-iodophenyl)-3-(R,S) methylpentadecanoic acid ((123)I-BMIPP) scintigraphy showed moderately reduced tracer uptake in the postero-inferior area on single-photon emission computed tomography and decreased washout on the planar images. After parathyroidectomy, the plasma levels of PTH and BNP decreased, followed by improvement in LV contraction. Myocardial (123)I-BMIPP scintigraphy revealed that the washout on planar images had increased, which suggests that myocardial (123)I-BMIPP scintigraphy is useful for estimating the effect of parathyroidectomy on cardiac function.
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Authors | Mamoru Nanasato, Norihiko Goto, Satoshi Isobe, Kazumasa Unno, Haruo Hirayama, Tetsuhiko Sato, Susumu Matsuoka, Takaharu Nagasaka, Yoshihiro Tominaga, Kazuharu Uchida, Toyoaki Murohara |
Journal | Circulation journal : official journal of the Japanese Circulation Society
(Circ J)
Vol. 73
Issue 10
Pg. 1956-60
(Oct 2009)
ISSN: 1347-4820 [Electronic] Japan |
PMID | 19179778
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Biomarkers
- Fatty Acids
- Iodine Radioisotopes
- Iodobenzenes
- Parathyroid Hormone
- Radiopharmaceuticals
- iodofiltic acid
- Natriuretic Peptide, Brain
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Topics |
- Biomarkers
(blood)
- Echocardiography
- Fatty Acids
(metabolism)
- Female
- Humans
- Hyperparathyroidism, Secondary
(etiology, metabolism, surgery)
- Iodine Radioisotopes
- Iodobenzenes
- Kidney Failure, Chronic
(complications, metabolism, therapy)
- Middle Aged
- Myocardial Contraction
- Myocardium
(metabolism)
- Natriuretic Peptide, Brain
(blood)
- Parathyroid Hormone
(blood)
- Parathyroidectomy
- Radiopharmaceuticals
- Recovery of Function
- Renal Dialysis
- Stroke Volume
- Tomography, Emission-Computed, Single-Photon
- Treatment Outcome
- Ventricular Dysfunction, Left
(diagnostic imaging, etiology, metabolism, physiopathology)
- Ventricular Function, Left
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