Evaluation of fasting and postprandial total serum bile acid concentration in dogs with hepatobiliary disorders.

Abstract

The fasting and 2 h postprandial total serum bile acid concentrations (FSBA and PSBA), alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, bilirubin (Total), and retention of bromosulphthalein were determined in a group of dogs with various hepatobiliary disorders as well as in a group of dogs with other diseases than hepatobiliary disorders. Although FSBA and PSBA were generally elevated in cases of hepatobiliary disorders, no distinction between different disease groups could be made based solely on FSBA and PSBA. FSBA and PSBA were found to be relatively sensitive and specific parameters compared to the other hepatic tests. PSBA tended to be superior to the other parameters investigated in terms of sensitivity, specificity, positive predictive value, and negative predictive value.

• Authors: A L Jensen
• Journal: Zentralblatt fur Veterinarmedizin. Reihe A (Zentralbl Veterinarmed A) Vol. 38 Issue 4 Pg. 247-54 (May 1991) ISSN: 0514-7158 [Print] Germany
• PMID: 1907782 (Publication Type: Journal Article)

Chemical References

• Bile Acids and Salts
• Corn Oil

Topics

• Animals
• Bile Acids and Salts (blood)
• Biliary Tract Diseases (blood, veterinary)
• Corn Oil (administration & dosage)
• Dog Diseases (blood)
• Dogs
• Eating (physiology)
• Female
• Food Deprivation (physiology)
• Liver Diseases (blood, veterinary)
• Male