Cyberknife radiosurgery for squamous cell carcinoma of vulva after prior pelvic radiation therapy.

Abstract

Limited options exist for patients experiencing a local recurrence of vulvar malignancies after surgery and pelvic radiation. These recurrences often are associated with cancer-related skin desquamation and poor clinical outcomes. A new radiotherapeutic treatment modality for the previously irradiated patient is cyberknife radiosurgery, which uses a linear accelerator mounted on an industrial robotic arm to allow non-coplanar radiation therapy delivery with sub-millimeter precision. This study describes the first reported use of cyberknife radiosurgery for the treatment of recurrent vulvar cancer in three women.

• Authors: Charles Kunos, Vivian von Gruenigen, Steven Waggoner, James Brindle, Yuxia Zhang, Brenda Myers, Gary Funkhouser, Barry Wessels, Douglas Einstein
• Journal: Technology in cancer research & treatment (Technol Cancer Res Treat) Vol. 7 Issue 5 Pg. 375-80 (Oct 2008) ISSN: 1533-0346 [Print] United States
• PMID: 18783287 (Publication Type: Case Reports, Journal Article, Research Support, N.I.H., Extramural)

Topics

• Aged, 80 and over
• Carcinoma, Squamous Cell (radiotherapy, surgery)
• Female
• Humans
• Particle Accelerators
• Pelvis (radiation effects)
• Radiosurgery (instrumentation, methods)
• Radiotherapy (methods)
• Radiotherapy Dosage
• Radiotherapy Planning, Computer-Assisted
• Recurrence
• Robotics
• Treatment Outcome
• Vulvar Neoplasms (radiotherapy, surgery)