[Basal ganglia deep-brain stimulation for treatment of drug-resistant epilepsy: review and current data].

Abstract

The surgical treatment of intractable epilepsies involving eloquent areas of the cortex is still challenging. Deep-brain stimulation could be an alternative to resective surgery because it can modulate the remote control systems of epilepsy, such as the thalamus and basal ganglia. The surgical experience acquired in the field of movement disorder surgery and the low morbidity of this technic could allow one to apply DBS to intractable epilepsies, such as generalized, motor and bitemporal epilepsies. Here we discuss the main experimental and clinical data reported so far in the literature and taken from our own experience.

• Authors: S Chabardès, L Minotti, S Chassagnon, B Piallat, N Torres, E Seigneuret, L Vercueil, R Carron, E Hirsch, P Kahane, A L Benabid
• Journal: Neuro-Chirurgie (Neurochirurgie) Vol. 54 Issue 3 Pg. 436-40 (May 2008) ISSN: 0028-3770 [Print] France
• Vernacular Title: La stimulation cérébrale profonde des ganglions de la base comme traitement des épilepsies pharmacorésistantes: revue et données actuelles.
• PMID: 18452956 (Publication Type: English Abstract, Journal Article, Review)

Topics

• Animals
• Basal Ganglia (physiology)
• Deep Brain Stimulation (adverse effects)
• Epilepsy (physiopathology, therapy)
• Humans
• Neurosurgical Procedures
• Thalamus (physiology, physiopathology)