Abstract |
An autosomal recessive disorder, Laron-type dwarfism, results from peripheral unresponsiveness to growth hormone. Mutations in the growth hormone receptor have recently been identified in this syndrome. Analysis of patients with Laron-type dwarfism should provide insight into the mechanisms of hormone receptor binding and signal transduction pathways of this receptor, which belongs to a new class of transmembrane receptors.
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Authors | S Amselem, P Duquesnoy, M Goossens |
Journal | Trends in endocrinology and metabolism: TEM
(Trends Endocrinol Metab)
1991 Jan-Feb
Vol. 2
Issue 1
Pg. 35-40
ISSN: 1043-2760 [Print] United States |
PMID | 18411163
(Publication Type: Journal Article)
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