[Granulocyte transfusion for the treatment of prolonged pneumonia in a patient with MDS-RAEB-2 at allogeneic hematopoietic stem cell transplantation].

Abstract

We report that granulocyte transfusion (GTX) was effective for prolonged pneumonia at allogeneic bone marrow transplantation. A 58-year-old man with MDS-RAEB-2 was admitted to our hospital for allogeneic bone marrow transplantation. He was complicated with pneumonia, which was not improved with G-CSF and antibiotics. We therefore decided to perform a GTX transplantation. During the period of neutropenia, pneumonia did not deteriorate. A combination of allogeneic stem cell transplantation and GTX is expected not only to improve transplantation results but also to expand the adaptation for transplantation. However, detailed investigation of the effect of GTX in allogeneic stem cell transplantation should be performed, and more cases should be accumulated.

• Authors: Rena Morita, Satoshi Hashino, Shojiro Takahashi, Hiroe Kanamori, Masahiro Onozawa, Kaoru Kahata, Takeshi Kondo, Masahiro Imamura, Masahiro Asaka
• Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology (Rinsho Ketsueki) Vol. 49 Issue 2 Pg. 89-93 (Feb 2008) ISSN: 0485-1439 [Print] Japan
• PMID: 18341038 (Publication Type: Case Reports, English Abstract, Journal Article)

Topics

• Granulocytes (transplantation)
• Hematopoietic Stem Cell Transplantation
• Humans
• Male
• Middle Aged
• Myelodysplastic Syndromes (complications, therapy)
• Pneumonia (complications, therapy)
• Transplantation, Homologous
• Treatment Outcome