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[Digital ischemia of a patient with undifferentiated large cell lung cancer]

AbstractA Raynaud's phenomenon with acral ischemia till necrosis is a rare form of a paraneoplasia. We report about a woman with a metastatic lung cancer, who was admitted because of pain in her left hand with necrosis of the fingertips and of the fifth right toe. We started a treatment with the intravenous vasodilator Iloprost, but the necroses progressed to gangrene. The course of a paraneoplastic syndrome is often determined by the underlying malignoma and if the antineoplastic treatment is ineffective, the chances to treat the paraneoplasia may be limited.
AuthorsI Schmid, M Fliegner (Affiliation: Stadtspital Triemli, Zürich.)
JournalDer Internist (Internist (Berl)) Vol. 49 Issue 3 Pg. 346-8 (Mar 2008) ISSN: 1432-1289 [Electronic] Germany
Vernacular TitleDigitale Ischämien bei einer Patientin mit grosszelligem Lungenkarzinom.
PMID18214409 (Publication Type: Case Reports, English Abstract, Journal Article)
Topics
  • Carcinoma, Large Cell (complications, diagnosis, therapy)
  • Diagnosis, Differential
  • Female
  • Humans
  • Lung Neoplasms (diagnosis, therapy)
  • Middle Aged
  • Paraneoplastic Syndromes (diagnosis, therapy)
  • Raynaud Disease (diagnosis, etiology, therapy)