Narrowband UVB therapy as an effective treatment for Schamberg's disease.

Abstract

A 33-year-old man presented with a 3-month history of a widespread pigmented purpuric eruption over his trunk and limbs. The clinical presentation and histology were consistent with a diagnosis of Schamberg's disease. The rash initially cleared following a short course of oral prednisolone at 25 mg daily for 3 weeks, which was weaned over the subsequent 4 weeks. Topical mometasone furoate ointment 0.1% daily was also applied to active areas. The rash recurred when prednisolone was reduced to below 5 mg per day. To prevent a further recurrence with weaning prednisolone, narrowband UVB therapy was commenced three times per week. The patient was continued on UV therapy over the next 5 months. The rash would flare after 2 to 3 weeks without treatment. The frequency of UV therapy was weaned and the patient remained clear on as little as one treatment every 2 weeks. Any further reduction, however, was associated with a recurrence. Narrowband UVB therapy should be considered for difficult or persistent cases of pigmented purpuric eruption.

• Authors: Anita L Lasocki, Robert I Kelly
• Journal: The Australasian journal of dermatology (Australas J Dermatol) Vol. 49 Issue 1 Pg. 16-8 (Feb 2008) ISSN: 0004-8380 [Print] Australia
• PMID: 18186840 (Publication Type: Case Reports, Journal Article)

Chemical References

• Glucocorticoids

Topics

• Adult
• Glucocorticoids (administration & dosage)
• Humans
• Leg Dermatoses (pathology, therapy)
• Male
• Phototherapy (methods)
• Pigmentation Disorders (pathology, therapy)
• Purpura (pathology)
• Radiation Dosage
• Skin (pathology)