[Treatment of dry eye syndrome with lacrimal gel: a randomized multicenter study].

Abstract	The appearance on the French market of a carbomer tear substitute, Gel-Larmes, an original galenic form, constitutes a real therapeutic progress in the treatment of dry eye syndrome. An open randomized multicentric trial was conducted comparing the tolerance and efficacy of Gel-Larmes with those of eye drops containing chondroitin sulphate. The statistical analysis evidences an inferior average number of daily instillations for Gel-Larmes, its better efficacy on the symptoms as well as on the objective criteria: biomicroscopic examination, break-up time, rose Bengal test. The tolerance of the product is excellent and 81% of the patients express their wish to pursue Gel-Larmes versus 54% for the reference product.
Authors	L Laroche, M Arrata, G Brasseur, F Lagoutte, Y Le Mer, P Lumbroso, M Mercante, F Normand, D Rigal, S Roncin
Journal	Journal francais d'ophtalmologie (J Fr Ophtalmol) Vol. 14 Issue 5 Pg. 321-6 ( 1991) ISSN: 0181-5512 [Print] France
Vernacular Title	Traitement de la sécheresse oculaire par gel lacrymal: étude multicentrique randomisée.
PMID	1779103 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Multicenter Study, Randomized Controlled Trial)
Chemical References	Acrylic Resins Antiviral Agents Gels Ophthalmic Solutions carbopol 940
Topics	Acrylic Resins (therapeutic use) Adult Aged Aged, 80 and over Antiviral Agents (therapeutic use) Dry Eye Syndromes (drug therapy) Female Gels Humans Male Middle Aged Ophthalmic Solutions Time Factors

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