[Lipodystrophy syndrome in HIV-infected patients. Clinical and diagnostic features].

Abstract

After the introduction of HAART (Highly Active Anti-Retroviral Therapy) in patients infected with HIV, a new syndrome--Lipodystrophy syndrome--has been described, in 1998. Lipodystrophy syndrome in patients with HIV infection comprises several conditions: lipoatrophy, lipohypertrophy, mixed syndrome (lipoatrophy and lipohypertrophy), often associated with dyslipidemia and insulin resistance. Lipoatrophy and lipohypertrophy can occur independently, being associated with different constellations of host, disease and drug risk factors. Until a working clinical definition on HIV-related lipodystrophy syndrome is developed, it will be difficult to monitor patients and compare studies, because, at present, investigators, clinicians and patients have different working definitions.

• Authors: A Streinu-Cercel, Daniela Adriana Ion, Laura Ioana Chivu, R D Chivu
• Journal: Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi (Rev Med Chir Soc Med Nat Iasi) 2006 Jul-Sep Vol. 110 Issue 3 Pg. 521-5 ISSN: 0048-7848 [Print] Romania
• Vernacular Title: Sindromul lipodistrofic la pacienţii infectaţi HIV--elemente clinice şi de diagnostic.
• PMID: 17571539 (Publication Type: English Abstract, Journal Article, Review)

Topics

• Antiretroviral Therapy, Highly Active (adverse effects, methods)
• Dyslipidemias (chemically induced)
• HIV Infections (complications, drug therapy)
• HIV-Associated Lipodystrophy Syndrome (chemically induced, diagnosis)
• Humans
• Insulin Resistance
• Syndrome