Detection of brain metastasis at 3T: comparison among SE, IR-FSE and 3D-GRE sequences.
|
| Abstract |
The objective of this study is to compare the detectability of brain metastases at 3T among three contrast-enhanced sequences, spin-echo (SE) sequence, inversion recovery fast SE (IR-FSE) sequence (both with section thickness of 6 mm), and three-dimensional fast spoiled gradient-echo (3D fast SPGR) sequence with 1.4 mm isotropic voxel. First, phantom studies were performed to quantify the contrast-enhancement ratio (CER) with three sequences. In 21 consecutive patients with brain metastases, axial images of three sequences at 3T were obtained after administration of gadoteridol. Two neuroradiologists assessed the detectability of brain metastases for the three sequences. In the phantom study, no evident difference in the CER was demonstrated among three sequences. Significantly more brain metastases were detected with 3D fast SPGR than with SE and IR-FSE (a total of 97 lesions with 3D fast SPGR vs. 64 with SE and 63 with IR-FSE). In particular, 3D fast SPGR was superior to the other two sequences in detection of the small lesions (<3 mm). At 3T, the contrast-enhanced 3D fast SPGR with 1.4 mm isotropic voxel is clinically more valuable for detecting small brain metastases than the SE and IR-FSE with section thickness of 6 mm.
|
|---|---|
| Authors | Shingo Kakeda, Yukunori Korogi, Yasuhiro Hiai, Norihiro Ohnari, Junji Moriya, Koji Kamada, Mai Hanamiya, Toru Sato, Mika Kitajima |
| Journal | European radiology (Eur Radiol) Vol. 17 Issue 9 Pg. 2345-51 (Sep 2007) ISSN: 0938-7994 [Print] Germany |
| PMID | 17318603 (Publication Type: Comparative Study, Historical Article, Journal Article) |
| Chemical References |
|
| Topics |
|
Join CureHunter, for free Research Interface BASIC access!
Realize the full power of the drug-disease research graph!