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A severe case of neonatal toxic shock syndrome-like exanthematous disease with superantigen-induced high T cell response.

Abstract
Most newborn patients with a neonatal type of toxic shock syndrome (TSS), called neonatal TSS-like exanthematous disease (NTED), exhibit mild clinical symptoms. We present the case of a patient with NTED who exhibited exceptionally severe clinical symptoms and an adult-type T cell response to the causative toxin TSS toxin-1.
AuthorsMizuka Miki, Takehiko Uchiyama, Hidehito Kato, Hiroshi Nishida, Naoto Takahashi
JournalThe Pediatric infectious disease journal (Pediatr Infect Dis J) Vol. 25 Issue 10 Pg. 950-2 (Oct 2006) ISSN: 0891-3668 [Print] United States
PMID17006297 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Bacterial Toxins
  • Enterotoxins
  • Superantigens
  • enterotoxin F, Staphylococcal
Topics
  • Bacterial Toxins (immunology)
  • Enterotoxins (immunology)
  • Female
  • Flow Cytometry
  • Humans
  • Infant, Newborn
  • Shock, Septic (immunology, microbiology)
  • Staphylococcal Infections (immunology, microbiology)
  • Staphylococcus aureus (isolation & purification)
  • Superantigens (immunology)
  • T-Lymphocyte Subsets (immunology)
  • T-Lymphocytes (immunology)

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