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Drug evaluation: dronedarone, a novel non-iodinated anti-arrhythmic agent.

Abstract
sanofi-aventis (formerly Sanofi-Synthelabo) is developing the oral class III anti-arrhythmic agent dronedarone (Multaq) for the potential treatment and prevention of atrial fibrillation. In June 2005, sanofi-aventis submitted EU and US filings for atrial fibrillation. In October 2002, phase I trials for arrhythmia were reported to be ongoing in Japan.
AuthorsSylvie Sablayrolles, Bruno Le Grand
JournalCurrent opinion in investigational drugs (London, England : 2000) (Curr Opin Investig Drugs) Vol. 7 Issue 9 Pg. 842-9 (Sep 2006) ISSN: 1472-4472 [Print] England
PMID17002263 (Publication Type: Journal Article, Review)
Chemical References
  • Anti-Arrhythmia Agents
  • Dronedarone
  • Amiodarone
Topics
  • Amiodarone (adverse effects, analogs & derivatives, chemical synthesis, pharmacokinetics, pharmacology, therapeutic use)
  • Animals
  • Anti-Arrhythmia Agents (adverse effects, chemical synthesis, pharmacokinetics, pharmacology, therapeutic use)
  • Arrhythmias, Cardiac (drug therapy)
  • Atrial Fibrillation (drug therapy)
  • Clinical Trials, Phase I as Topic
  • Clinical Trials, Phase II as Topic
  • Clinical Trials, Phase III as Topic
  • Dronedarone
  • Humans

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