Silico-asbestosis that responded to steroid therapy.

Abstract

A 73-year-old man with silico-asbestosis responded to steroid therapy. Chest CT scans showed diffuse micronodular opacities and ground glass opacities bilaterally throughout the entire lung fields, as well as progressive massive fibrosis in the bilateral upper lung fields. Diagnostic thoracoscopic biopsy revealed mixed dust pneumoconiosis with silicotic nodules, as well as fibrosis similar to that of Usual Interstitial Pneumonia (UIP) with many fibroblastic foci and alveolitis. Many asbestos bodies were also detected by iron staining.

• Authors: Sakuo Hoshi, Yotaro Tamai, Atsushi Tamura, Hirofumi Ishida, Nozomi Yoshida, Chuhei Ogawa, Naoto Suzuki, Yasuyuki Sano, Yoshinori Kawabata
• Journal: Internal medicine (Tokyo, Japan) (Intern Med) Vol. 45 Issue 15 Pg. 917-21 ( 2006) ISSN: 1349-7235 [Electronic] Japan
• PMID: 16946575 (Publication Type: Case Reports, Journal Article)

Chemical References

• Prednisolone
• Methylprednisolone

Topics

• Aged
• Asbestosis (diagnostic imaging, drug therapy, etiology)
• Humans
• Male
• Methylprednisolone (therapeutic use)
• Prednisolone (therapeutic use)
• Radiography
• Silicosis (diagnostic imaging, drug therapy, etiology)