Abstract | PURPOSE: METHODS: This nonrandomized prospective study included 56 patients who were admitted with occlusive arterial disease (group I), and 39 control patients without occlusive arterial disease (group II). We recorded all the demographic data of both groups and collected blood samples for fasting homocysteine, vitamin B(12), and folic acid. All of the patients were followed up and the results were compared. RESULTS: The mean concentration of homocysteine was 12.69 +/- 3.82 micromol/l in group I and 10.46 +/- 5.08 micromol/l in group II (P = 0.00048). In group I, the mean homocysteine levels for patients aged > or =70 years and those aged <70 years were 13.74 +/- 3.02 and 11.55 +/- 4.15 micromol/l, respectively (P = 0.021). There was no significant difference in mortality between the patients with HHCA and those with normal homocysteine levels during follow-up. CONCLUSION:
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Authors | Murat Aksoy, Yilmaz Basar, Nihal Salmayenli, Kemal Ayalp, Fatih Ata Genc, Sukru Dilege, Murat Kayabali, Selcuk Baktiroglu, Mehmet Kurtoglu |
Journal | Surgery today
(Surg Today)
Vol. 36
Issue 4
Pg. 327-31
( 2006)
ISSN: 0941-1291 [Print] Japan |
PMID | 16554989
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Homocysteine
- Folic Acid
- Vitamin B 12
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Topics |
- Aged
- Aged, 80 and over
- Arterial Occlusive Diseases
(complications, physiopathology)
- Case-Control Studies
- Female
- Folic Acid
- Homocysteine
(blood)
- Humans
- Hyperhomocysteinemia
(complications, physiopathology)
- Male
- Middle Aged
- Prospective Studies
- Risk Assessment
- Risk Factors
- Vitamin B 12
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