[A comparison of the effects of laser and light-emitting diodes on superoxide dismutase activity and nitric oxide production in rat wound fluid].

Abstract

The action of laser and light-emitting diode radiation in the visible region on the content of reactive nitrogen species and activity of superoxide dismutase in rat wound fluid was studied, and efficiency of action of coherent laser and incoherent light emitting diode radiations in the red region of the spectrum on the parameters under study was compared. A model of incised aseptic wounds in rats proposed by L.I. Slutskiy was used. A He-Ne laser (632 nm) and a Y-332B light emitting diode served as radiation sources. It was shown that (1) exposure of wounds to the visible light of both laser and light-emitting diodes causes dose-dependent changes in superoxide dismutase activity and production of nitrites and (2) the radiation coherence does not play any significant role in the changes of superoxide dismutase activity or nitrogen oxide formation by wound fluid phagocytes.

• Authors: G I Klebanov, N Iu Shuraeva, T V Chichuk, A N Osipov, Iu A Vladimirov
• Journal: Biofizika (Biofizika) 2006 Jan-Feb Vol. 51 Issue 1 Pg. 116-22 ISSN: 0006-3029 [Print] Russia (Federation)
• PMID: 16521561 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Nitric Oxide
• Superoxide Dismutase

Topics

• Animals
• Exudates and Transudates (chemistry, cytology, metabolism)
• Lasers
• Leukocytes (chemistry, metabolism)
• Lightning
• Male
• Nitric Oxide (analysis, metabolism)
• Rats
• Rats, Inbred Strains
• Superoxide Dismutase (analysis, metabolism)
• Wound Healing (radiation effects)