[Activity of enzymes of galactose metabolism in so-called congenital cataract (author's transl)].

Abstract

Activity of galactokinase (69 subjects) and galactose-1-phosphate uridyl transferase (92 subjects) were measured in haemolysed blood from children (predominantly of school age) with congenital cataract. chi2 tests, gene-frequency determination and metabolic-kinetic studies indicated that the changes in the lens in congenital cataract are partly due to a manifest or latent disorder of galactose metabolism, in particular a glactose-1-phosphate uridyl transferase defect.

• Authors: H Kaloud, F C Sitzmann, H Schenker, H Prestele
• Journal: Deutsche medizinische Wochenschrift (1946) (Dtsch Med Wochenschr) Vol. 100 Issue 16 Pg. 873-6 (Apr 18 1975) ISSN: 0012-0472 [Print] Germany
• Vernacular Title: Enzymaktivitätswerte des Galaktosestoffwechsels bei der sogenannten Cataracta congenita
• PMID: 164335 (Publication Type: English Abstract, Journal Article)

Chemical References

• Phosphotransferases
• Galactose

Topics

• Austria
• Cataract (congenital, enzymology, metabolism, prevention & control)
• Child
• Child, Preschool
• Diet Therapy
• Galactose (metabolism)
• Gene Frequency
• Humans
• Infant
• Methods
• Phosphotransferases (blood)