Abstract |
We report an HIV-positive patient who developed a unilateral retinitis and subsequent intracranial lesions. The finding of Epstein Barr virus (EBV) DNA at a > 1-log greater concentration in the vitreous compared to blood raised the possibility of a primary CNS non-Hodgkin's lymphoma, which was subsequently confirmed on brain biopsy. EBV DNA quantification acted as a diagnostic marker that led to a change in the management of our patient.
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Authors | Shu Fen Ho, Colin Fink, Philip I Murray |
Journal | Ocular immunology and inflammation
(Ocul Immunol Inflamm)
Vol. 13
Issue 6
Pg. 471-3
(Dec 2005)
ISSN: 0927-3948 [Print] England |
PMID | 16321894
(Publication Type: Case Reports, Journal Article)
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Chemical References |
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Topics |
- Adult
- Brain Neoplasms
(complications, diagnosis, virology)
- DNA, Viral
(genetics)
- Diagnosis, Differential
- Herpesvirus 4, Human
(genetics)
- Humans
- Lymphoma, AIDS-Related
(complications, diagnosis, virology)
- Male
- Polymerase Chain Reaction
- Retinitis
(diagnosis, etiology)
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