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Epstein-Barr Virus DNA quantification: an adjunctive diagnostic marker for AIDS-associated lymphoma.

Abstract
We report an HIV-positive patient who developed a unilateral retinitis and subsequent intracranial lesions. The finding of Epstein Barr virus (EBV) DNA at a > 1-log greater concentration in the vitreous compared to blood raised the possibility of a primary CNS non-Hodgkin's lymphoma, which was subsequently confirmed on brain biopsy. EBV DNA quantification acted as a diagnostic marker that led to a change in the management of our patient.
AuthorsShu Fen Ho, Colin Fink, Philip I Murray
JournalOcular immunology and inflammation (Ocul Immunol Inflamm) Vol. 13 Issue 6 Pg. 471-3 (Dec 2005) ISSN: 0927-3948 [Print] England
PMID16321894 (Publication Type: Case Reports, Journal Article)
Chemical References
  • DNA, Viral
Topics
  • Adult
  • Brain Neoplasms (complications, diagnosis, virology)
  • DNA, Viral (genetics)
  • Diagnosis, Differential
  • Herpesvirus 4, Human (genetics)
  • Humans
  • Lymphoma, AIDS-Related (complications, diagnosis, virology)
  • Male
  • Polymerase Chain Reaction
  • Retinitis (diagnosis, etiology)

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