Abstract | OBJECTIVE: METHODS: RESULTS: (1) The serum positive rate of HCMV- IgM and HCMV- IgG in the ACS, SA and healthy control groups were 30.4% (24/79), 10.0% (3/30) and 6.7% (2/30); 86.1% (68/79), 80.0% (24/30) and 53.3% (16/30), respectively. Positive rate of HCMV- IgM in the ACS was higher than those in SA and healthy control groups (P < 0.01), positive rate of HCMV- IgG in the ACS and SA groups were higher than that of the healthy control group (P < 0.01). (2) Compared with the SA group and healthy control group, the levels of the serum soluble P-selectin and TNF-alpha were significantly higher in patients with ACS [(6437.3 +/- 666.9) pg/ml vs. (1520.0 +/- 112.7) pg/ml and (1481.0 +/- 109.1) pg/ml, (56.2 +/- 18.4) pg/ml vs. (27.3 +/- 13.7) pg/ml and (28.1 +/- 11.3) pg/ml], respectively, P < 0.01). The AMI group, compared with the UA group in the ACS group, had significantly higher levels of the serum soluble P-selectin and TNF-alpha (P < 0.01). Compared with the SA group, the levels of the serum soluble P-selectin and TNF-alpha were not significantly different in healthy control group. (3) The levels of the serum soluble P-selectin and TNF-alpha in HCMV- IgM positive patients were significantly higher than the HCMV- IgM negative patients in the ACS group (P < 0.01). CONCLUSION:
|
Authors | Xiao-ming Wang, Yuan Li, Chen Huang, Rong-huai Zhang, Hai-tao Guo, Hao Chen, Hai-chang Wang |
Journal | Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology
(Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi)
Vol. 19
Issue 2
Pg. 149-51
(Jun 2005)
ISSN: 1003-9279 [Print] China |
PMID | 16027783
(Publication Type: English Abstract, Journal Article, Research Support, Non-U.S. Gov't)
|
Chemical References |
- Immunoglobulin M
- P-Selectin
- Tumor Necrosis Factor-alpha
|
Topics |
- Acute Coronary Syndrome
(blood, virology)
- Adult
- Aged
- Aged, 80 and over
- Cytomegalovirus
(immunology, physiology)
- Cytomegalovirus Infections
(blood, virology)
- Enzyme-Linked Immunosorbent Assay
- Female
- Host-Pathogen Interactions
- Humans
- Immunoglobulin M
(blood)
- Male
- Middle Aged
- P-Selectin
(blood)
- Tumor Necrosis Factor-alpha
(blood)
|