Can chronic subthalamic nucleus stimulation induce de novo tremor in Parkinson's disease?

Abstract

Subthalamic nucleus stimulation dramatically improves parkinsonian symptoms, notably the tremor. The occurrence of a tremor in the first 6 months after the surgical procedure in patients without tremor preoperatively is much less common. We report on the cases of 3 patients who developed such modification of their parkinsonian symptomatology. Physiopathological hypotheses are discussed.

• Authors: Stephane Thobois, Stephen Tisch, Jing Xie-Brustolin, Patrick Mertens, Marwan I Hariz, Isabelle Benatru, Emmanuel Broussolle, Patricia Limousin-Dowsey
• Journal: Movement disorders : official journal of the Movement Disorder Society (Mov Disord) Vol. 20 Issue 8 Pg. 1066-9 (Aug 2005) ISSN: 0885-3185 [Print] United States
• PMID: 15852367 (Publication Type: Case Reports, Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: Copyright 2005 Movement Disorder Society

Topics

• Aged
• Deep Brain Stimulation (adverse effects)
• Female
• Follow-Up Studies
• Humans
• Male
• Middle Aged
• Parkinson Disease (surgery)
• Subthalamic Nucleus (physiopathology, radiation effects)
• Tremor (etiology)