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A systematic review of the effectiveness of anticalculus dentifrices.

AbstractPURPOSE:
To assess the evidence on the effectiveness of commercially available anticalculus dentifrices.
MATERIALS AND METHODS:
Systematic search for published and unpublished epidemiological data in 7 electronic databases, 5 journals, and the bibliographies of retrieved papers and by making contact with subject experts in this field. Thirty-two reports were identified containing comparisons of one or more active agents with a placebo dentifrice and calculus measured using the Volpe-Manhold Index (VMI).
RESULTS:
Random effect model for 3-month studies showed an effect size of -0.6 for all comparisons. The effect sizes varied from -0.3 for dentifrices with zinc chloride 0.5% to -1.1 for pyrophosphate 1.3% and copolymer 1.5% dentifrices. Meta-analysis of all the studies with 6-month follow-up gave an effect size of -1.1 (-1.5 to -0.8) and for 12-month follow-up the effect size was -13.6 (-21.4 to -5.8).
CONCLUSIONS:
Anticalculus dentifrices containing pyrophosphates, zinc compounds and/or co-polymers were effective in significantly reducing calculus scores (VMI).
AuthorsGopalakrishnan S Netuveli, Aubrey Sheiham
JournalOral health & preventive dentistry (Oral Health Prev Dent) Vol. 2 Issue 1 Pg. 49-58 ( 2004) ISSN: 1602-1622 [Print] Germany
PMID15641765 (Publication Type: Journal Article, Meta-Analysis, Review, Systematic Review)
Chemical References
  • Dentifrices
  • Diphosphates
  • Maleates
  • Polyethylenes
  • poly(methyl vinyl ether-co-maleic anhydride)
Topics
  • Dental Calculus (prevention & control)
  • Dentifrices (therapeutic use)
  • Diphosphates (therapeutic use)
  • Humans
  • Maleates (therapeutic use)
  • Polyethylenes (therapeutic use)
  • Toothbrushing (methods)
  • Treatment Outcome

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