diphosphoric acid (pyrophosphoric acid)

10/01/1978 - "Studies have shown that technetium-99m stannous pyrophosphate (Tc-PPi) is effective for the detection and imaging of acute myocardial infarction. "
01/01/1981 - "Pyrophosphate scintigraphy: improved detection of the acute myocardial infarction with computer data manipulation and Fourier method analysis."
07/01/1987 - "In order to determine the feasibility of using this agent in clinical studies and to compare the agent to technetium-99m pyrophosphate (Tc-99m PPi), ten patients with proven myocardial infarction were studied. "
01/01/1978 - "This study suggests that technetium-99m pyrophosphate scintigraphy can defect acute myocardial infarction as early as 4 hours after the onset of symptoms although the sensitivity rate (73 percent) is less than that at 24 hours."
12/01/1977 - "Clinicopathologic study of persistently positive technetium-99m stannous pyrophosphate myocardial scintigrams and myocytolytic degeneration after myocardial infarction."

11/15/2000 - "This article describes the structure of polypyrophosphate as compared to the parent pyrophosphate molecule, the rationale for its improved chemistry, and, in particular, its tartar control chemistry. "
01/01/1987 - "Effects of pyrophosphate/copolymer/NaF on dental calculus and caries formation in vivo."
12/01/1970 - "The concentration of inorganic pyrophosphate in human saliva and dental calculus."
11/15/2000 - "Lastly, a preliminary clinical study evaluating the improved efficacy of a polypyrophosphate dentifrice is described where the tartar control activity of the polypyrophosphate dentifrice is shown to be superior to that of a clinically established and marketed industry standard pyrophosphate dentifrice."
01/01/1998 - "Safety and efficacy of a novel tartar control dentifrice containing 3.3% pyrophosphate: a controlled six-month clinical trial."

06/01/1989 - "The mouthrinse containing only soluble pyrophosphate did not provide a statistically significant reduction in calculus deposits, as compared to the placebo mouthrinse."
01/01/2009 - "Prevention of lingual calculus formation with daily use of 6% H2O2/2% pyrophosphate whitening strips."
12/01/2001 - "The pyrophosphate content was dependent on the calculi composition. "
01/01/1998 - "The final results demonstrated that the pyrophosphate floss significantly inhibited calculus formation between teeth (mesial-distal scores) by 21%, and on labial surfaces by 37% relative to the placebo floss."
02/01/1993 - "A double-blind, cross-over study was carried out to assess the anti-calculus effectiveness of a pyrophosphate containing cleaning gel. "

06/01/1987 - "Cross-sectional echocardiography is superior to pyrophosphate scintigraphy for recognition of cardiac amyloidosis."
10/27/2023 - "Additionally, clinical experiences of Tc-99m pyrophosphate imaging have recently gained attention for assessing cardiac amyloidosis. "
05/01/2023 - "An outpatient workup confirmed the diagnosis of amyloidosis with a positive pyrophosphate scan. "
12/01/2022 - "Multimodality imaging with cardiac MRI and technetium-99m pyrophosphate scintigraphy (PYP) during this hospital course revealed concurrent cardiac amyloidosis. "
09/01/2022 - "The imaging protocol and the optimal cut-off points for quantitative assessment of technetium-99m pyrophosphate (Tc-99m PYP) cardiac amyloidosis scintigraphy remain controversial. "

12/01/1984 - "The present study evaluates 46 patients with different infarct distributions and sizes to test the hypothesis that single photon emission computed tomography with technetium-99m pyrophosphate (Tc-99m-PPi) and blood pool overlay allows measurements of AMI size that provide insight into prognosis irrespective of infarct location. "
07/01/1977 - "The present study was performed in order to evaluate the ability of technetium-99m stannous pyrophosphate (99mTc-PYP) myocardial scintigrams to size infarcts in experimental animals and man. "
07/01/1999 - "Tc-99m pyrophosphate is the grandfather of infarct avid agents. "
03/01/1996 - "The QRS0 was correlated with the extent of the Tl-201 perfusion defect (r = 0.79, p < 0.001), and the day 7 QRS score was correlated with Tc-99m pyrophosphate infarct size (r = 0.79, p < 0.005). "
03/01/1996 - "Subsequent Tc-99m pyrophosphate infarct size was 15 +/- 9% of the left ventricle for anterior and 17 +/- 9% for inferior infarcts. "