Abstract | OBJECTIVE: In 2003, critical care and infectious disease experts representing 11 international organizations developed management guidelines for other supportive therapies in sepsis that would be of practical use for the bedside clinician, under the auspices of the Surviving Sepsis Campaign, an international effort to increase awareness and improve outcome in severe sepsis. DESIGN: The process included a modified Delphi method, a consensus conference, several subsequent smaller meetings of subgroups and key individuals, teleconferences, and electronic-based discussion among subgroups and among the entire committee. METHODS: The modified Delphi methodology used for grading recommendations built on a 2001 publication sponsored by the International Sepsis Forum. We undertook a systematic review of the literature graded along five levels to create recommendation grades from A to E, with A being the highest grade. Pediatric considerations to contrast adult and pediatric management are in the article by Parker et al. on p. S591. CONCLUSION:
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Authors | Stephen Trzeciak, R Phillip Dellinger |
Journal | Critical care medicine
(Crit Care Med)
Vol. 32
Issue 11 Suppl
Pg. S571-7
(Nov 2004)
ISSN: 0090-3493 [Print] United States |
PMID | 15542966
(Publication Type: Journal Article, Review, Systematic Review)
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Topics |
- Consensus Development Conferences as Topic
- Evidence-Based Medicine
- Humans
- Peptic Ulcer
(prevention & control)
- Practice Guidelines as Topic
- Sepsis
(complications, therapy)
- Stress, Physiological
(complications)
- Venous Thrombosis
(prevention & control)
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