A case of listerial meningitis treated with a regimen containing panipenem-betamipron.

Abstract

Although panipenem-betamipron, which is commercially available only in Japan, is recommended for treatment of pediatric bacterial meningitis by some experts, only a limited number of clinical studies have been reported. In the present report, we describe a 2-year-old boy with meningitis caused by Listeria monocytogenes who was treated with a regimen containing panipenem-betamipron and recovered without any apparent neurological sequelae. On the basis of our experience and previous reports, panipenem-betamipron appears to be effective for the treatment of listerial meningitis.

• Authors: Shigemi Hitomi, Tatsuyuki Ohto, Miho Okamoto, Yoko Nishimura, Nobuyuki Iwasaki, Akira Matsui
• Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy (J Infect Chemother) Vol. 10 Issue 4 Pg. 242-4 (Aug 2004) ISSN: 1341-321X [Print] Netherlands
• PMID: 15365867 (Publication Type: Case Reports, Journal Article)

Chemical References

• Anti-Bacterial Agents
• Thienamycins
• beta-Alanine
• panipenem-betamipron

Topics

• Anti-Bacterial Agents (therapeutic use)
• Child, Preschool
• Humans
• Listeria monocytogenes (drug effects)
• Male
• Meningitis, Listeria (drug therapy, microbiology)
• Thienamycins (therapeutic use)
• Treatment Outcome
• beta-Alanine (analogs & derivatives, therapeutic use)