Effect of highly active antiretroviral therapy on cardiovascular involvement in children with human immunodeficiency virus infection.

Abstract	The impact of highly active antiretroviral therapy (HAART) on cardiovascular involvement was evaluated in 38 vertically human immunodeficiency virus-infected children followed up for 5 years. This study demonstrates for the first time in a cohort of children the resolution of previous dilated cardiomyopathy after the start of HAART and the absence of cardiovascular events related to metabolic abnormalities during the period of its administration.
Authors	Anna Plebani, Susanna Esposito, Raffaella Pinzani, Vlasta Fesslova, Jelena Bojanin, Patrizia Salice, Matteo Rossi, Nicola Principi
Journal	The Pediatric infectious disease journal (Pediatr Infect Dis J) Vol. 23 Issue 6 Pg. 559-63 (Jun 2004) ISSN: 0891-3668 [Print] United States
PMID	15194840 (Publication Type: Comparative Study, Journal Article)
Topics	Age Distribution Analysis of Variance Antiretroviral Therapy, Highly Active (adverse effects, methods) Cardiovascular Diseases (chemically induced, diagnosis, epidemiology) Child Child, Preschool Cohort Studies Dose-Response Relationship, Drug Drug Administration Schedule Echocardiography Electrocardiography Female HIV Infections (congenital, drug therapy) Humans Incidence Italy (epidemiology) Longitudinal Studies Male Probability Prognosis Risk Assessment Severity of Illness Index Sex Distribution

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