Functional evaluation of lung by Xe-133 lung ventilation scintigraphy before and after lung volume reduction surgery (LVRS) in patients with pulmonary emphysema.

Abstract

We evaluated the respiratory functions of patients with pulmonary emphysema who underwent lung volume reduction surgery (LVRS) by the mean transit time (MTT) with Xe-133 lung ventilation scintigraphy, forced expiration volume in 1 sec (FEV1.0), residual volume (RV), distance walked in 6 min (6-min walk), and the Hugh-Jones classification (H-J classification) before and after LVRS. In 69 patients with pulmonary emphysema (62 men, 7 women; age range, 47-75 years; mean age, 65.4 years +/- 6.1, preoperative H-J classification, III (two were II)-V) who underwent LVRS, all preoperative and postoperative parameters (MTT 3 weeks after LVRS and the others 3 months after LVRS) were judged statistically by the Wilcoxon signed-ranks test and Odds ratio. Every postoperative parameter was improved with a significant difference (P < 0.05) compared to preoperative parameters. MTT at 3 weeks after LVRS was not associated with %FEV1.0 and the H-J classification at 3 months after LVRS, but was associated with RV and a 6-min walk at 3 months after LVRS. MTT was useful for the clinical evalution of aerobic capability after LVRS.

• Authors: Taichi Kurose, Yoshihiro Okumura, Shuhei Sato, Yasuhiro Yamamoto, Shiro Akaki, Yoshihiro Takeda, Susumu Kanazawa, Akio Ando, Hiroshi Date, Nobuyoshi Shimizu, Yoshio Hiraki
• Journal: Acta medica Okayama (Acta Med Okayama) Vol. 58 Issue 1 Pg. 7-15 (Feb 2004) ISSN: 0386-300X [Print] Japan
• PMID: 15157006 (Publication Type: Journal Article)

Chemical References

• Xenon Radioisotopes

Topics

• Aged
• Female
• Humans
• Lung (metabolism, surgery)
• Lung Volume Measurements
• Male
• Middle Aged
• Pneumonectomy
• Pulmonary Emphysema (metabolism, physiopathology, surgery)
• Radionuclide Imaging
• Respiratory Function Tests
• Treatment Outcome
• Walking
• Xenon Radioisotopes (metabolism)