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Pulmonary Emphysema

Enlargement of air spaces distal to the TERMINAL BRONCHIOLES where gas-exchange normally takes place. This is usually due to destruction of the alveolar wall. Pulmonary emphysema can be classified by the location and distribution of the lesions.
Also Known As:
Centriacinar Emphysema; Centrilobular Emphysema; Emphysemas, Pulmonary; Focal Emphysema; Panacinar Emphysema; Panlobular Emphysema; Pulmonary Emphysemas; Centriacinar Emphysemas; Centrilobular Emphysemas; Emphysema, Centriacinar; Emphysema, Centrilobular; Emphysema, Focal; Emphysema, Panacinar; Emphysema, Panlobular; Emphysemas, Centriacinar; Emphysemas, Centrilobular; Emphysemas, Focal; Emphysemas, Panacinar; Emphysemas, Panlobular; Focal Emphysemas; Panacinar Emphysemas; Panlobular Emphysemas; Emphysema, Pulmonary
Networked: 1452 relevant articles (51 outcomes, 129 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Chronic Obstructive Pulmonary Disease (COPD)
2. Emphysema
3. Lung Diseases (Lung Disease)
4. Asthma (Bronchial Asthma)
5. Bronchitis

Experts

1. Ma, Shuren: 7 articles (01/2021 - 05/2005)
2. Turino, Gerard M: 7 articles (01/2021 - 02/2002)
3. Aoshiba, Kazutetsu: 7 articles (01/2017 - 03/2004)
4. Takahashi, Kazuhisa: 6 articles (01/2022 - 09/2006)
5. Cantor, Jerome O: 6 articles (01/2021 - 02/2002)
6. Elias, Jack A: 6 articles (01/2021 - 05/2005)
7. Lee, Chun Geun: 6 articles (01/2021 - 05/2005)
8. Tanaka, Ken-Ichiro: 6 articles (01/2019 - 09/2011)
9. Seyama, Kuniaki: 5 articles (01/2022 - 09/2006)
10. Shapiro, Steven D: 5 articles (01/2020 - 03/2003)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Pulmonary Emphysema:
1. Pancreatic Elastase (Elastase)IBA
2. SmokeIBA
3. PapainIBA
4. Leukocyte Elastase (Neutrophil Elastase)IBA
5. Tretinoin (Retinoic Acid)FDA LinkGeneric
6. Serine Proteinase Inhibitors (Serine Protease Inhibitors)IBA
7. Theophylline (Theon)FDA LinkGeneric
8. EnzymesIBA
9. Matrix Metalloproteinases (MMPs)IBA
10. CollagenIBA

Therapies and Procedures

1. Pneumonectomy (Lung Volume Reduction)
2. Therapeutics
3. Transplantation
4. Cell- and Tissue-Based Therapy (Cell Therapy)
5. Lung Transplantation