Schistosomiasis does not contribute to death or recurrence of nontyphoid Salmonella bacteremia in human immunodeficiency virus-infected Malawian adults.

Abstract

Nontyphoid Salmonella (NTS) bacteremia has a very high mortality and recurrence rate among human immunodeficiency virus (HIV)-infected Malawian adults. Concurrent schistosomal infection might cause persistence of NTS infection and poor response to antibiotic therapy. Therefore, we tested serum samples for Schistosoma-specific circulating anodic antigen to diagnose coinfection with schistosomiasis among consecutive HIV-positive adults with NTS bacteremia. The results suggest that active schistosomiasis is not associated with adverse outcome of NTS bacteremia in this population, in contrast to other groups.

• Authors: Melita A Gordon, Eduard E Zijlstra, Cynthia W A Naus, Leo G Visser, Malcolm E Molyneux, Lisette van Lieshout
• Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (Clin Infect Dis) Vol. 37 Issue 12 Pg. e177-9 (Dec 15 2003) ISSN: 1537-6591 [Electronic] United States
• PMID: 14689364 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Antigens, Helminth
• Glycoproteins
• Helminth Proteins
• circulating anodic antigen, Schistosoma mansoni

Topics

• Adult
• Animals
• Antigens, Helminth (blood)
• Bacteremia (complications, mortality)
• Female
• Glycoproteins (blood)
• HIV
• HIV Infections (complications, mortality)
• Helminth Proteins (blood)
• Humans
• Male
• Salmonella Infections (complications, mortality)
• Schistosomiasis (complications, mortality)
• Treatment Outcome