Abstract | OBJECTIVE: METHODS: RESULTS: Using LPA test, an etiological diagnosis could be made in 83% cases of bacterial meningitis. In contrast, CSF Gram stain and culture showed 36% and 6% positivity, respectively. The sensitivity and specificity of LPA test were 83% and 100%, respectively. The common etiological organisms were S. pneumoniae, H. influenzae type b and N. meningitidis A. S. pneumoniae was encountered in all age groups while H. influenzae type b was found only below one year of age. CONCLUSIONS: LPA test is a rapid and superior diagnostic tool as compared to CSF Gram stain and culture. The study recommends LPA test as an adjunct laboratory test for rapid etiological diagnosis of bacterial meningitis for prompt institution of proper antibiotics.
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Authors | B K Das, Rajesh Lal Gurubacharya, T M Mohapatra, O P Mishra |
Journal | Indian journal of pediatrics
(Indian J Pediatr)
Vol. 70
Issue 10
Pg. 799-801
(Oct 2003)
ISSN: 0019-5456 [Print] India |
PMID | 14649475
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Adolescent
- Antigens, Bacterial
(cerebrospinal fluid, immunology)
- Child
- Child, Preschool
- Humans
- Infant
- Latex Fixation Tests
(instrumentation)
- Meningitis, Bacterial
(cerebrospinal fluid, immunology, microbiology)
- Sensitivity and Specificity
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