[An evaluation of the quality of tetanus anatoxins by gel electrophoresis].

Abstract

The study of tetanus toxoids obtained from different manufacturers in the USSR has shown that these preparations exhibit molecular heterogeneity. The method of gel filtration has made it possible to find out that tetanus toxoids from different manufacturers differ in the degree of their purification. The preparations produced by the manufacturing enterprises in Perm and Ufa have been found to contain considerably less ballast substances than the preparations produced in Moscow.

• Authors: V F Runova, T M Kargina, F F Rezepov, V P Selezneva, E M Legat, V L Plotnikova
• Journal: Zhurnal mikrobiologii, epidemiologii i immunobiologii (Zh Mikrobiol Epidemiol Immunobiol) Issue 2 Pg. 38-40 (Feb 1992) ISSN: 0372-9311 [Print] Russia (Federation)
• Vernacular Title: Otsenka kachestva stolbniachnykh anatoksinov metodom gel'-fil'tratsii.
• PMID: 1441810 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Tetanus Toxoid

Topics

• Calibration
• Chromatography, Gel (instrumentation, methods)
• Counterimmunoelectrophoresis (methods)
• Evaluation Studies as Topic
• Quality Control
• Tetanus Toxoid (analysis, isolation & purification, standards)
• USSR