[Diagnosis and therapeutics of placental site trophoblastic tumor].

Abstract

OBJECTIVE:

In order to get better understanding of placental site trophoblastic tumor (PSTT), we have investigated 4 PSTT cases that diagnosed in our hospital and with literature reviews.

METHODS:

We identified 4 patients of PSTT in our choriocarcinoma ward from Jan, 1985 to Dec, 2000 by retrospective analysis.

RESULTS:

PSTT accounted for 3.1@1000 of all trophoblastic diseases, the ratio of PSTT to choriocarcinoma was 1:138. The average age was 31. Two cases were secondary to hydatidiform mole with paremetrial or pulmonary metastasis respectively. All cases received hysterectomy and multiple chemotherapy. With a follow-up of 29 to 84 months, all patients are survived up to now.

CONCLUSIONS:

PSTT is a rare gestational trophoblastic tumor. Accurate pathological diagnosis is critical for proper treatment. The diagnosis and monitor are rather difficult because the beta-hCG are non-parallel to the growth and disappearance of the tumor. Operation plays an important role in its treatment, and multiple chemotherapy is helpful.

• Authors: Shan Deng, Xiu-yu Yang
• Journal: Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae (Zhongguo Yi Xue Ke Xue Yuan Xue Bao) Vol. 24 Issue 4 Pg. 418-21 (Aug 2002) ISSN: 1000-503X [Print] China
• PMID: 12905666 (Publication Type: English Abstract, Journal Article)

Chemical References

• Chorionic Gonadotropin, beta Subunit, Human

Topics

• Adult
• Chorionic Gonadotropin, beta Subunit, Human (blood)
• Female
• Follow-Up Studies
• Humans
• Pregnancy
• Retrospective Studies
• Trophoblastic Tumor, Placental Site (diagnosis, surgery)
• Uterine Neoplasms (diagnosis, surgery)