Abstract | BACKGROUND: We describe, for the first time, the occurrence of two pure examples of spindle cell neoplasm with fibrous and smooth muscle differentiation in the larynx. MATERIALS AND METHOD: RESULTS:
Tumors were seen as raised submucosal nodules in the glottic region of two elderly male patients. Histopathologically, the lesions were unencapsulated and composed of spindle cells that manifested variable cellular anaplasia and expressed SMA and were negative for keratin, S-100, and h- Caldesmon. CONCLUSIONS: We document histologically low-grade malignant myofibroblastic tumors of the larynx. Complete excision is advised.
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Authors | Allison R MacGregor, John G Batsakis, Adel K El-Naggar |
Journal | Head & neck
(Head Neck)
Vol. 25
Issue 7
Pg. 606-11
(Jul 2003)
ISSN: 1043-3074 [Print] United States |
PMID | 12808665
(Publication Type: Case Reports, Journal Article)
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Copyright | Copyright 2003 Wiley Periodicals, Inc. Head Neck 25: 606-611, 2003 |
Topics |
- Aged
- Humans
- Laryngeal Neoplasms
(pathology, surgery)
- Male
- Neoplasms, Muscle Tissue
(pathology, surgery)
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