Early and definitive diagnosis of toxic shock syndrome by detection of marked expansion of T-cell-receptor VBeta2-positive T cells.

Abstract

We describe two cases of early toxic shock syndrome, caused by the superantigen produced from methicillin-resistant Staphylococcus aureus and diagnosed on the basis of an expansion of T-cell-receptor VBeta2-positive T cells. One case-patient showed atypical symptoms. Our results indicate that diagnostic systems incorporating laboratory techniques are essential for rapid, definitive diagnosis of toxic shock syndrome.

• Authors: Yoshio Matsuda, Hidehito Kato, Ritsuko Yamada, Hiroya Okano, Hiroaki Ohta, Ken'ichi Imanishi, Ken Kikuchi, Kyouichi Totsuka, Takehiko Uchiyama
• Journal: Emerging infectious diseases (Emerg Infect Dis) Vol. 9 Issue 3 Pg. 387-9 (Mar 2003) ISSN: 1080-6040 [Print] United States
• PMID: 12643839 (Publication Type: Case Reports, Journal Article)

Chemical References

• Bacterial Toxins
• Enterotoxins
• Superantigens
• enterotoxin F, Staphylococcal

Topics

• Adult
• Bacterial Toxins
• Enterotoxins (blood)
• Female
• Humans
• Puerperal Infection (diagnosis, microbiology)
• Shock, Septic (diagnosis)
• Superantigens