[Detection of interleukin-6 in gingival crevicular fluid from active and non-active adult periodontitis sites].

Abstract

OBJECTIVE:

To reveal the relationship between IL-6 and the activity of periodontitis.

METHODS:

The concentration of IL-6 in gingival crevicular fluid (GCF) was measure by ELISA. Sixty teeth from 39 patients with adult periodontitis were sampled, among which there were 29 teeth in active phase, while the rest were in non-active phase.

RESULTS:

Significant difference was found in the level of IL-6 in GCF between the active group (10.65 +/- 22.05 ng/ml) and the non-active group (1.73 +/- 0.53 ng/ml, P < 0.05).

CONCLUSION:

The level of IL-6 in GCF may be a useful indicator of the activity of periodontitis.

• Authors: C Zhao, Y Wu, J Zhang, P Huang
• Journal: Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao (Hua Xi Yi Ke Da Xue Xue Bao) Vol. 32 Issue 3 Pg. 444-5 (Sep 2001) ISSN: 0257-7712 [Print] China
• PMID: 12536589 (Publication Type: Comparative Study, English Abstract, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Biomarkers
• Interleukin-6

Topics

• Adult
• Biomarkers (analysis)
• Enzyme-Linked Immunosorbent Assay
• Female
• Gingival Crevicular Fluid (chemistry)
• Humans
• Interleukin-6 (analysis)
• Male
• Periodontitis (metabolism)